IC87201

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Selleck Chemicals

E7648

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IC87201 is an inhibitor of NMDAR used in studies of Calcium Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to calcium flux, excitability, and secretion-linked signaling in neuroscience models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By inhibiting NMDAR, IC87201 can be used to examine calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving NMDAR
  • Pathway perturbation studies connected to Calcium Signaling
  • Concentration-response inhibition and target-dependence studies
  • Electrophysiology, ion-flux, and membrane-potential studies

Overall, IC87201 is appropriate when a defined chemical perturbant is needed to connect NMDAR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
NMDAR
Target Class:
Ion Channel
Pathways:
Calcium Signaling
Research Area:
Neuroscience
CAS No.:
866927-10-8
Molecular Weight:
309.15
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.