Idarubicin HCl

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Selleck Chemicals

S1228-5MG

€144,00 EUR
€144,00 EUR
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Idarubicin HCl is a modulator of Topoisomerase used in studies of PI3K-Akt-mTOR Signaling and DNA Damage Response and related signaling programs. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint activation, DNA repair, and genome-stability control in autophagy, cancer, and dna damage / repair models.

By modulating Topoisomerase, Idarubicin HCl can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and dna damage / repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Topoisomerase
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and DNA Damage Response and related signaling programs
  • Context-dependent response profiling and mechanism comparison
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Idarubicin HCl is appropriate when a defined chemical perturbant is needed to connect Topoisomerase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and dna damage / repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Topoisomerase
Target Class:
Enzyme
Pathways:
PI3K-Akt-mTOR Signaling • DNA Damage Response • Autophagy
Research Area:
Autophagy • Cancer • DNA Damage / Repair • Infectious Disease
CAS No.:
57852-57-0
Molecular Weight:
533.95
Formula:
C₂₆H₂₇NO₉·HCl
SMILES:
CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.