Insulin receptor (INSR or CD220) Antibody
BiCell Scientific
SKU:52090-50UL
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About the Target
Designed to help you assess Insulin receptor, this antibody supports studies where protein context matters. Insulin receptor is a signaling protein that can relay information through phosphorylation and complex assembly. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol INSR.
Research Context
When comparing conditions, consistent sample handling and normalization are key for meaningful contrasts. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- time-resolved changes following stimulation or inhibition
- localization shifts between cytoplasm, membrane, and nucleus
- condition-to-condition comparisons with matched controls
Variant Considerations
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Insulin receptor patterns can be compared across experiments without guesswork.
If your study spans multiple model systems, it can help to define a shared reference condition for Insulin receptor so cross-sample contrasts stay meaningful.
As you refine hypotheses around Insulin receptor, the regular format format helps keep conclusions tied to preparation context.
- Targets:
- INSR
- Research Area:
- Cell Signaling • Developmental Biology • Endocrinology • Immunology • Metabolism
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the C-terminal region of mouse INSR protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P06213
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 94.1% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C