INT-767

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Selleck Chemicals

E5874-5MG

€193,00 EUR
€193,00 EUR
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INT-767 is an agonist of FXR used in studies of Hormone Signaling and Metabolic Signaling. In practice, this places the compound in experiments that measure ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology, immunology, and inflammation models.

By activating FXR, INT-767 can be used to examine ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving FXR
  • Pathway perturbation studies connected to Hormone Signaling and Metabolic Signaling
  • Agonist-response and downstream signaling studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, INT-767 is appropriate when a defined chemical perturbant is needed to connect FXR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
FXR
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling • Metabolic Signaling
Research Area:
Endocrinology • Immunology • Inflammation • Metabolism
CAS No.:
1000403-03-1
Molecular Weight:
495.67
Formula:
C₂₅H₄₄O₆S·Na
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.