Integrin alpha-2 (ITGA2 or CD49b) Antibody
BiCell Scientific
SKU:10002-50UL
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Scientific Overview
Bring Integrin alpha-2 (ITGA2) into view to examine changes across conditions. Integrin alpha-2 is an extracellular or receptor-linked component that coordinates matrix engagement with cytoskeletal remodeling. Focus on trends across conditions rather than single-point snapshots.
Tracking Integrin alpha-2 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Relevance
Matrix-interaction targets are often evaluated under changing substrate stiffness or ligand composition. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling.
When building a narrative around the target, it helps to track:
- focal adhesion versus diffuse membrane distribution
- effects of adhesion inhibitors or matrix composition
- remodeling after changes in substrate or mechanical stress
- co-variation with cytoskeletal and scaffold partners
Application-Specific Context
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
When interpreting Integrin alpha-2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
For challenging targets, pairing Integrin alpha-2 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Choose the regular format option when you want Integrin alpha-2 (ITGA2) results aligned to your sample format.
- Targets:
- ITGA2
- Research Area:
- Developmental Biology • Immunology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the C-terminal region of human integrin alpha-2 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P17301
- Homology:
- Synthetic peptide sequence is 84.6% homologous to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C