Integrin alpha-L (ITGAL or CD11a) Antibody

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BiCell Scientific

SKU:10012-50UL

Regular price €305,00 EUR
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Size
Blocking Peptide
Quantity
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Protein Function

This antibody enables you to investigate Integrin alpha-L with a direct, biology-first readout. Integrin alpha-L is an extracellular or receptor-linked component that coordinates matrix engagement with cytoskeletal remodeling. Look for shifts in distribution that track with phenotype changes.

Tracking Integrin alpha-L can clarify whether changes reflect regulation, redistribution, or altered complex assembly.

Experimental Applications

Perturbations that disrupt integrin engagement or actomyosin tension can reshape localization and complex assembly. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

In practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy.

Common experimental questions that benefit from target tracking include:

  • focal adhesion versus diffuse membrane distribution
  • effects of adhesion inhibitors or matrix composition
  • remodeling after changes in substrate or mechanical stress
  • co-variation with cytoskeletal and scaffold partners

Workflow Perspective

If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.

If your study spans multiple model systems, it can help to define a shared reference condition for Integrin alpha-L so cross-sample contrasts stay meaningful.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Integrin alpha-L patterns can be compared across experiments without guesswork.

Select the regular format version to keep Integrin alpha-L interpretation aligned with your workflow goals.

Targets:
ITGAL
Research Area:
Developmental Biology • Immunology
Application:
IF • IHC • WB
Reactivity:
Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (13-aa) derived from the C-terminal cytoplasmic region of mouse integrin alpha-L protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
P20701
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 30.8% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C