Integrin alpha-L (ITGAL or CD11a) Antibody
BiCell Scientific
SKU:10012-50UL
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Protein Function
This antibody enables you to investigate Integrin alpha-L with a direct, biology-first readout. Integrin alpha-L is an extracellular or receptor-linked component that coordinates matrix engagement with cytoskeletal remodeling. Look for shifts in distribution that track with phenotype changes.
Tracking Integrin alpha-L can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Experimental Applications
Perturbations that disrupt integrin engagement or actomyosin tension can reshape localization and complex assembly. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
In practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy.
Common experimental questions that benefit from target tracking include:
- focal adhesion versus diffuse membrane distribution
- effects of adhesion inhibitors or matrix composition
- remodeling after changes in substrate or mechanical stress
- co-variation with cytoskeletal and scaffold partners
Workflow Perspective
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.
If your study spans multiple model systems, it can help to define a shared reference condition for Integrin alpha-L so cross-sample contrasts stay meaningful.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Integrin alpha-L patterns can be compared across experiments without guesswork.
Select the regular format version to keep Integrin alpha-L interpretation aligned with your workflow goals.
- Targets:
- ITGAL
- Research Area:
- Developmental Biology • Immunology
- Application:
- IF • IHC • WB
- Reactivity:
- Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the C-terminal cytoplasmic region of mouse integrin alpha-L protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P20701
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 30.8% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C