Integrin alpha-V (ITGAV or CD51) Antibody

About the Target

Plan your comparisons around Integrin alpha-V and use this antibody to analyze state-dependent differences. Integrin alpha-V is a matrix-interaction protein often examined in migration and morphogenesis models. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.

In some datasets and protocols, it is referenced by the gene symbol CD51.

Research Context

Matrix-interaction targets are often evaluated under changing substrate stiffness or ligand composition. Time course design can be decisive when regulation is transient or compartment dependent.

Consider these angles when interpreting target-level changes:

• co-variation with cytoskeletal and scaffold partners
• effects of adhesion inhibitors or matrix composition
• focal adhesion versus diffuse membrane distribution

Variant Considerations

This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. This matters because epitope exposure and background can vary with preparation and extraction steps. Include controls that separate true target shifts from matrix or preparation effects.

For challenging targets, pairing Integrin alpha-V measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

For challenging targets, pairing Integrin alpha-V measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

Integrate the regular format version into your design so Integrin alpha-V signals can be interpreted alongside matched controls.