Integrin beta-4 (ITGB4 or CD104) Antibody - FFPE Validated

Scientific Overview

Use this antibody to evaluate Integrin beta-4 (ITGB4) in your model system. Integrin beta-4 is a matrix-interaction protein often examined in migration and morphogenesis models. Look for shifts in distribution that track with phenotype changes.

In some datasets and protocols, it is referenced by the gene symbol ITGB4.

Research Relevance

Comparative experiments can separate expression differences from changes in adhesion structure abundance. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood.

When building a narrative around the target, it helps to track:

• focal adhesion versus diffuse membrane distribution
• co-variation with cytoskeletal and scaffold partners
• remodeling after changes in substrate or mechanical stress
• effects of adhesion inhibitors or matrix composition

Application-Specific Context

In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.

If your study spans multiple model systems, it can help to define a shared reference condition for Integrin beta-4 so cross-sample contrasts stay meaningful.

If your study spans multiple model systems, it can help to define a shared reference condition for Integrin beta-4 so cross-sample contrasts stay meaningful.

With a clear focus on Integrin beta-4 (ITGB4), this fixed-section option fits streamlined studies and fast iteration.