Integrin beta-6 (ITGB6) Antibody
BiCell Scientific
SKU:10026-50UL
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Scientific Overview
This antibody enables you to characterize Integrin beta-6 (ITGB6) with a direct, biology-first readout. Integrin beta-6 is a cell-surface or matrix-associated protein that mediates adhesion and outside-in signaling. Focus on trends across conditions rather than single-point snapshots.
Following Integrin beta-6 across perturbations can help separate expression effects from compartment shifts.
Research Relevance
Perturbations that disrupt integrin engagement or actomyosin tension can reshape localization and complex assembly. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.
When building a narrative around the target, it helps to track:
- focal adhesion versus diffuse membrane distribution
- co-variation with cytoskeletal and scaffold partners
- effects of adhesion inhibitors or matrix composition
- remodeling after changes in substrate or mechanical stress
Application-Specific Context
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
For challenging targets, pairing Integrin beta-6 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
For challenging targets, pairing Integrin beta-6 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Select the regular format version to keep Integrin beta-6 (ITGB6) interpretation aligned with your workflow goals.
- Targets:
- ITGB6
- Research Area:
- Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the C-terminal region of mouse integrin beta-6 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P18564
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 83.3% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C