Integrin beta-7 (ITGB7) Antibody
BiCell Scientific
SKU:10027-50UL
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About the Target
When you need to evaluate Integrin beta-7 with attention to cellular organization, this antibody provides a focused option. Integrin beta-7 is an extracellular or receptor-linked component that coordinates matrix engagement with cytoskeletal remodeling. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Monitoring Integrin beta-7 alongside context markers can improve interpretation when phenotypes are subtle.
Research Context
Perturbations that disrupt integrin engagement or actomyosin tension can reshape localization and complex assembly. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- focal adhesion versus diffuse membrane distribution
- remodeling after changes in substrate or mechanical stress
- effects of adhesion inhibitors or matrix composition
Variant Considerations
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
For challenging targets, pairing Integrin beta-7 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
If your study spans multiple model systems, it can help to define a shared reference condition for Integrin beta-7 so cross-sample contrasts stay meaningful.
The regular format version supports deeper biological narratives around Integrin beta-7 without overcomplicating setup.
- Targets:
- ITGB7
- Research Area:
- Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the C-terminal region of human integrin beta-7 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P26010
- Homology:
- Synthetic peptide sequence showing 83.3% homology to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C