Ipragliflozin (ASP1941)

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Selleck Chemicals

S8637-5MG

€154,00 EUR
€154,00 EUR
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Ipragliflozin (ASP1941) is an inhibitor of SGLT and SGLT2 used in studies of GPCR Signaling and Metabolic Signaling. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology and metabolism models.

By inhibiting SGLT and SGLT2, Ipragliflozin (ASP1941) can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The transporter annotation adds relevance to transport, uptake/efflux, and permeability assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving SGLT and SGLT2
  • Pathway perturbation studies connected to GPCR Signaling and Metabolic Signaling
  • Concentration-response inhibition and target-dependence studies
  • Transport, uptake/efflux, and permeability assays

Overall, Ipragliflozin (ASP1941) is appropriate when a defined chemical perturbant is needed to connect SGLT and SGLT2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
SGLT • SGLT2
Target Class:
Transporter
Pathways:
GPCR Signaling • Metabolic Signaling
Research Area:
Endocrinology • Metabolism
CAS No.:
761423-87-4
Molecular Weight:
404.45
Formula:
C₂₁H₂₁FOS
SMILES:
C1=CC=C2C(=C1)C=C(S2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)F
InChIKey:
AHFWIQIYAXSLBA-UHFFFAOYSA-N
PubChem:
10453870
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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