Isoliquiritin apioside

1 1

Selleck Chemicals

S0923-1MG

€124,00 EUR
€124,00 EUR
Sale Sold out
Taxes included. Shipping calculated at checkout.
Size
View full details

Isoliquiritin apioside is an inhibitor of MMP and NF-kB used in studies of MAPK / ERK Signaling and NF-kB Signaling and related signaling programs. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and inflammatory transcriptional control and stress-responsive survival signaling in cancer, immunology, and inflammation models.

By inhibiting MMP and NF-kB, Isoliquiritin apioside can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and inflammatory transcriptional control and stress-responsive survival signaling. The protease annotation adds relevance to protease-activity, cleavage, and substrate-processing assays, together with downstream-response mapping in the same experimental setting. In cancer, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving MMP and NF-kB
  • Pathway perturbation studies connected to MAPK / ERK Signaling and NF-kB Signaling and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Protease-activity, cleavage, and substrate-processing assays

Overall, Isoliquiritin apioside is appropriate when a defined chemical perturbant is needed to connect MMP and NF-kB with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
MMP • NF-kB
Target Class:
Protease
Pathways:
MAPK / ERK Signaling • NF-kB Signaling • Immune Signaling
Research Area:
Cancer • Immunology • Inflammation
CAS No.:
120926-46-7
Molecular Weight:
550.51
Formula:
C₂₆H₃₀O₁₃
SMILES:
C1C(C(C(O1)OC2C(C(C(OC2OC3=CC=C(C=C3)C=CC(=O)C4=C(C=C(C=C4)O)O)CO)O)O)O)(CO)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.