Ispinesib (SB-715992)

1 1

Selleck Chemicals

S1452-1MG

€144,00 EUR
€144,00 EUR
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Ispinesib (SB-715992) is an inhibitor of Kinesins used in studies of Cell Cycle Regulation. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to checkpoint control, mitotic progression, and proliferation timing in cancer and cell cycle models.

By inhibiting Kinesins, Ispinesib (SB-715992) can be used to examine checkpoint control, mitotic progression, and proliferation timing. This context is compatible with cell-cycle, mitotic, and proliferation assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cancer and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Kinesins
  • Pathway perturbation studies connected to Cell Cycle Regulation
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in cancer and cell cycle models

Overall, Ispinesib (SB-715992) is appropriate when a defined chemical perturbant is needed to connect Kinesins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Kinesins
Target Class:
Other
Pathways:
Cell Cycle Regulation
Research Area:
Cancer • Cell Cycle
CAS No.:
336113-53-2
Molecular Weight:
517.06
Formula:
C₃₀H₃₃ClN₄O₂
SMILES:
CC1=CC=C(C=C1)C(=O)N(CCCN)C(C2=NC3=C(C=CC(=C3)Cl)C(=O)N2CC4=CC=CC=C4)C(C)C
InChIKey:
QJZRFPJCWMNVAV-UHFFFAOYSA-N
PubChem:
6851740
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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