JNJ 63533054

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Selleck Chemicals

SKU:S6425-5MG

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JNJ 63533054 is an agonist of GPR used in studies of GPCR Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to receptor-driven second-messenger signaling and desensitization dynamics in cell signaling models.

By activating GPR, JNJ 63533054 can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving GPR
  • Pathway perturbation studies connected to GPCR Signaling
  • Agonist-response and downstream signaling studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, JNJ 63533054 is appropriate when a defined chemical perturbant is needed to connect GPR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
GPR
Target Class:
GPCR
Pathways:
GPCR Signaling
Research Area:
Cell Signaling
CAS No.:
1802326-66-4
Molecular Weight:
316.78
Formula:
C₁₇H₁₇ClN₂O₂
SMILES:
CC(C1=CC=CC=C1)NC(=O)CNC(=O)C2=CC(=CC=C2)Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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