JNJ-7706621
Selleck Chemicals
SKU:S1249-1MG
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JNJ-7706621 is an inhibitor of CDK and Aurora Kinases used in studies of Cell Cycle Regulation. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to checkpoint control, mitotic progression, and proliferation timing in cancer, cell cycle, and cell signaling models.
By inhibiting CDK and Aurora Kinases, JNJ-7706621 can be used to examine checkpoint control, mitotic progression, and proliferation timing. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving CDK and Aurora Kinases
- Pathway perturbation studies connected to Cell Cycle Regulation
- Concentration-response inhibition and target-dependence studies
- Biochemical kinase assays, phospho-signaling studies, and selectivity profiling
Overall, JNJ-7706621 is appropriate when a defined chemical perturbant is needed to connect CDK and Aurora Kinases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- CDK • Aurora Kinases
- Target Class:
- Kinase
- Pathways:
- Cell Cycle Regulation
- Research Area:
- Cancer • Cell Cycle • Cell Signaling
- CAS No.:
- 443797-96-4
- Molecular Weight:
- 394.36
- Formula:
- C₁₅H₁₂F₂N₆O₃S
- SMILES:
- C1=CC(=C(C(=C1)F)C(=O)N2C(=NC(=N2)NC3=CC=C(C=C3)S(=O)(=O)N)N)F
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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