JTE 013

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Selleck Chemicals

S7182-10MG

€144,00 EUR
€144,00 EUR
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JTE 013 is an antagonist of S1P Receptors used in studies of GPCR Signaling. It is especially relevant in immunology and inflammation models, where defined compound exposure can be linked to receptor-driven second-messenger signaling and desensitization dynamics.

By blocking S1P Receptors, JTE 013 can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving S1P Receptors
  • Pathway perturbation studies connected to GPCR Signaling
  • Receptor-blockade and ligand-competition studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, JTE 013 is appropriate when a defined chemical perturbant is needed to connect S1P Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
S1P Receptors
Target Class:
GPCR
Pathways:
GPCR Signaling
Research Area:
Immunology • Inflammation
CAS No.:
383150-41-2
Molecular Weight:
408.29
Formula:
C₁₇H₁₉Cl₂N₇O
SMILES:
CC1=NN(C2=C1C(=CC(=N2)NNC(=O)NC3=CC(=NC(=C3)Cl)Cl)C(C)C)C
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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