K-Ras (G12C)inhibitor 12
Selleck Chemicals
SKU:S7331-5MG
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K-Ras (G12C)inhibitor 12 is an inhibitor of KRAS used in studies of MAPK / ERK Signaling. It is especially relevant in cancer, cell cycle, and cell signaling models, where defined compound exposure can be linked to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling.
By inhibiting KRAS, K-Ras (G12C)inhibitor 12 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. This context is compatible with phosphorylation mapping, pathway-response, and growth assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving KRAS
- Pathway perturbation studies connected to MAPK / ERK Signaling
- Concentration-response inhibition and target-dependence studies
- Phenotypic profiling in cancer, cell cycle, and cell signaling models
Overall, K-Ras (G12C)inhibitor 12 is appropriate when a defined chemical perturbant is needed to connect KRAS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- KRAS
- Target Class:
- Other
- Pathways:
- MAPK / ERK Signaling
- Research Area:
- Cancer • Cell Cycle • Cell Signaling
- CAS No.:
- 1469337-95-8
- Molecular Weight:
- 449.67
- Formula:
- C₁₅H₁₇ClIN₃O₃
- SMILES:
- C=CC(=O)N1CCN(CC1)C(=O)CNC2=CC(=C(C=C2O)Cl)I
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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