KB-R7943 mesylate

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Selleck Chemicals

S4643-5MG

€105,00 EUR
€105,00 EUR
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KB-R7943 mesylate is an inhibitor of NCX used in studies of MAPK / ERK Signaling and Calcium Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and calcium flux, excitability, and secretion-linked signaling in cardiovascular and cell signaling models.

By inhibiting NCX, KB-R7943 mesylate can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and calcium flux, excitability, and secretion-linked signaling. The transporter annotation adds relevance to transport, uptake/efflux, and permeability assays, together with downstream-response mapping in the same experimental setting. In cardiovascular and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving NCX
  • Pathway perturbation studies connected to MAPK / ERK Signaling and Calcium Signaling
  • Concentration-response inhibition and target-dependence studies
  • Transport, uptake/efflux, and permeability assays

Overall, KB-R7943 mesylate is appropriate when a defined chemical perturbant is needed to connect NCX with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
NCX
Target Class:
Transporter
Pathways:
MAPK / ERK Signaling • Calcium Signaling
Research Area:
Cardiovascular • Cell Signaling
CAS No.:
182004-65-5
Molecular Weight:
427.5
Formula:
C₁₇H₂₁N₃O₆S₂
SMILES:
C[S](O)(=O)=O.NC(=N)SCCC1=CC=C(OCC2=CC=C(C=C2)[N+]([O-])=O)C=C1
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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