KCNA4 (Kv1.4) Antibody
BiCell Scientific
SKU:20224-50UL
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Scientific Overview
To connect mechanism with measurement, this antibody lets you assess KCNA4 in pathway-driven studies. KCNA4 is a membrane protein linked to solute movement and gradient maintenance. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Tracking KCNA4 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Relevance
Comparisons across tissues or engineered cell lines can help separate expression effects from localization effects. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling.
When building a narrative around the target, it helps to track:
- relative abundance across engineered constructs
- patterns consistent with apical or basolateral sorting
- stimulus-dependent trafficking and turnover
Application-Specific Context
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. If signaling is transient, sampling time can be as important as condition.
For challenging targets, pairing KCNA4 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Use the regular format version to relate KCNA4 behavior to upstream cues and downstream consequences.
- Targets:
- KCNA4
- Research Area:
- Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal region of human Kv1.4 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P22459
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C