KCNA7 (Kv1.7) Antibody - Western Blot Validated
BiCell Scientific
SKU:20227-WB-50UL
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Scientific Overview
For consistent comparison across experiments, use this antibody to explore KCNA7 with a repeatable workflow. KCNA7 is a membrane-embedded regulator of ionic or osmotic balance in cells. Use matched handling so differences reflect biology rather than processing.
Monitoring KCNA7 alongside context markers can improve interpretation when phenotypes are subtle.
Research Relevance
Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling.
When building a narrative around the target, it helps to track:
- surface versus intracellular pool distribution
- stimulus-dependent trafficking and turnover
- relative abundance across engineered constructs
- patterns consistent with apical or basolateral sorting
Application-Specific Context
For size-resolved readouts under denaturing conditions, this version helps you focus on expected band patterns and molecular weight regions. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. A short pilot series can help set exposure ranges and reduce reruns.
If your study spans multiple model systems, it can help to define a shared reference condition for KCNA7 so cross-sample contrasts stay meaningful.
For multi-run studies, the denaturing-format option helps keep KCNA7 trends comparable from experiment to experiment.
- Targets:
- KCNA7
- Research Area:
- Neuroscience
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal region of mouse Kv1.7 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q96RP8
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 85.7% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C