KCNB2 (Kv2.2) Antibody

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BiCell Scientific

SKU:20232-50UL

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Size
Blocking Peptide
Quantity
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About the Target

This antibody supports efforts to assess KCNB2 and interpret it within interaction networks. KCNB2 is a channel or transporter associated with regulated flux across cellular membranes. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.

Monitoring KCNB2 alongside context markers can improve interpretation when phenotypes are subtle.

Research Context

Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.

Consider these angles when interpreting target-level changes:

  • stimulus-dependent trafficking and turnover
  • relative abundance across engineered constructs
  • surface versus intracellular pool distribution

Variant Considerations

This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.

When interpreting KCNB2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so KCNB2 patterns can be compared across experiments without guesswork.

Choose the regular format format to study KCNB2 in a way that stays anchored to pathway logic.

Targets:
KCNB2
Research Area:
Neuroscience
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (14-aa) derived from the C-terminal region of mouse Kv2.2 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
Q92953
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 92.9% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C