KCNC3 (Kv3.3) Antibody
BiCell Scientific
SKU:20237-50UL
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Scientific Overview
This antibody is suited for researchers who want to evaluate KCNC3 and relate it to cell-state biology. KCNC3 is a membrane protein linked to solute movement and gradient maintenance. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Following KCNC3 across perturbations can help separate expression effects from compartment shifts.
Research Relevance
Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
When building a narrative around the target, it helps to track:
- surface versus intracellular pool distribution
- patterns consistent with apical or basolateral sorting
- stimulus-dependent trafficking and turnover
Application-Specific Context
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
When interpreting KCNC3, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Use the regular format variant when your project demands KCNC3 readouts that respect preparation constraints.
- Targets:
- KCNC3
- Research Area:
- Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal region of mouse Kv3.3 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q14003
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 50% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C