KCNC3 (Kv3.3) Antibody - FFPE Validated

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BiCell Scientific

SKU:20237-FFPE-50UL

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Size
Blocking Peptide
Quantity
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Protein Function

Use this antibody to characterize KCNC3 when mapping complex behavior and signaling context. KCNC3 is a membrane-embedded regulator of ionic or osmotic balance in cells. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.

Following KCNC3 across perturbations can help separate expression effects from compartment shifts.

Experimental Applications

Many transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.

In practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy. Neural differentiation and synaptic organization projects may include this target as a contextual readout.

Common experimental questions that benefit from target tracking include:

  • stimulus-dependent trafficking and turnover
  • surface versus intracellular pool distribution
  • patterns consistent with apical or basolateral sorting

Workflow Perspective

In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. If interactions are a focus, consider parallel readouts for key partners.

When interpreting KCNC3, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

The fixed-section option supports mechanistic reading of KCNC3 when interactions and context are the focus.

Targets:
KCNC3
Research Area:
Neuroscience
Application:
IHC-P
Reactivity:
Mouse • Rat
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (14-aa) derived from the C-terminal region of mouse Kv3.3 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
Q14003
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 50% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C