KCND1 (Kv4.1) Antibody
BiCell Scientific
SKU:20241-50UL
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About the Target
Build reproducible readouts by using this antibody to explore KCND1 across matched sample sets. KCND1 is a channel or transporter associated with regulated flux across cellular membranes. For comparison-heavy studies, consistent sample handling and normalization help reduce run-to-run drift.
Tracking KCND1 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Context
Transport targets are commonly studied under stimulation conditions that alter membrane potential, osmolarity, or nutrient availability. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.
Consider these angles when interpreting target-level changes:
- stimulus-dependent trafficking and turnover
- surface versus intracellular pool distribution
- relative abundance across engineered constructs
- patterns consistent with apical or basolateral sorting
Variant Considerations
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. This matters because epitope exposure and background can vary with preparation and extraction steps. Standardize key parameters so differences reflect biology rather than handling.
For challenging targets, pairing KCND1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so KCND1 patterns can be compared across experiments without guesswork.
For multi-run studies, the regular format option helps keep KCND1 trends comparable from experiment to experiment.
- Targets:
- KCND1
- Research Area:
- Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (12-aa) derived from the C-terminal region of mouse Kv4.1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9NSA2
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 91.7% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C