KDM2B (JHDM1B) Antibody - Western Blot Validated
BiCell Scientific
SKU:82104-WB-50UL
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Scientific Overview
To connect mechanism with measurement, this antibody lets you explore KDM2B in pathway-driven studies. KDM2B is a target that supports characterization of cellular state through expression and localization readouts. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
In some datasets and protocols, it is referenced by the gene symbol JHDM1B.
Research Relevance
In many projects, target-level measurements help link perturbations to downstream phenotypes. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.
When building a narrative around the target, it helps to track:
- interpretation alongside orthogonal readouts
- subcellular compartment mapping
- cross-sample normalization strategies
Application-Specific Context
For size-resolved readouts under denaturing conditions, this version helps you focus on expected band patterns and molecular weight regions. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. If signaling is transient, sampling time can be as important as condition.
When interpreting KDM2B, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
For challenging targets, pairing KDM2B measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Use the denaturing-format version to relate KDM2B behavior to upstream cues and downstream consequences.
- Targets:
- KDM2B
- Research Area:
- Epigenetics
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the C-terminal region of human KDM2B protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q8NHM5
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.