KIAA0408 (C-Terminus) Antibody - FFPE Validated

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BiCell Scientific

SKU:90710C-FFPE-50UL

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Size
Blocking Peptide
Quantity
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About the Target

This antibody is suited for researchers who want to characterize KIAA0408 C-Terminus and relate it to cell-state biology. KIAA0408 C-Terminus is a microtubule-organizing element often evaluated in cell-cycle and cilia studies. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.

Monitoring KIAA0408 C-Terminus alongside context markers can improve interpretation when phenotypes are subtle.

Research Context

Disruption of intraflagellar transport or basal body function can produce distinct localization signatures. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.

Consider these angles when interpreting target-level changes:

  • changes in cilia incidence or apparent length in perturbation studies
  • cell-cycle linked differences in localization
  • co-occurrence with intraflagellar transport markers

Variant Considerations

This fixed-section oriented version is intended for paraffin-embedded tissue, where crosslinking and retrieval steps can shape epitope accessibility. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so KIAA0408 C-Terminus patterns can be compared across experiments without guesswork.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so KIAA0408 C-Terminus patterns can be compared across experiments without guesswork.

The fixed-section version supports deeper biological narratives around KIAA0408 C-Terminus without overcomplicating setup.

Targets:
KIAA0408
Research Area:
Cell Cycle • Developmental Biology
Application:
IHC-P
Reactivity:
Human
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (16-aa) derived from the C-terminal region of human KIAA0408 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
Q6ZU52
Homology:
Synthetic peptide sequence is identical to monkey sequence (rodents having no homologue to human KIAA0408 gene)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C