KIAA0586 (TALPID3) (Human) (N-Terminus) Antibody
BiCell Scientific
SKU:90711-50UL
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Scientific Overview
This antibody enables you to explore KIAA0586 N-Terminus with a direct, biology-first readout. KIAA0586 N-Terminus is a microtubule-organizing element often evaluated in cell-cycle and cilia studies. Focus on trends across conditions rather than single-point snapshots.
In some datasets and protocols, it is referenced by the gene symbol TALPID3.
Research Relevance
Quantitative comparisons often rely on consistent imaging parameters and clear inclusion criteria for ciliated cells. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.
When building a narrative around the target, it helps to track:
- co-occurrence with intraflagellar transport markers
- cell-cycle linked differences in localization
- changes in cilia incidence or apparent length in perturbation studies
- signal enrichment at basal bodies versus cytoplasm
Application-Specific Context
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
If your study spans multiple model systems, it can help to define a shared reference condition for KIAA0586 N-Terminus so cross-sample contrasts stay meaningful.
When interpreting KIAA0586 N-Terminus, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
With a clear focus on KIAA0586 N-Terminus, this regular format option fits streamlined studies and fast iteration.
- Targets:
- KIAA0586
- Research Area:
- Cell Cycle • Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the N-terminal region of human KIAA0586 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9BVV6
- Homology:
- Synthetic peptide sequence shows 56.3% homology to mouse sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C