KIAA0586 (TALPID3) (Human) (N-Terminus) Antibody - Western Blot Validated
BiCell Scientific
SKU:90711-WB-50UL
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About the Target
This antibody is suited for researchers who want to analyze KIAA0586 N-Terminus and relate it to cell-state biology. KIAA0586 N-Terminus is a trafficking-related component that can localize to basal bodies and ciliary axonemes. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Tracking KIAA0586 N-Terminus can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Context
Quantitative comparisons often rely on consistent imaging parameters and clear inclusion criteria for ciliated cells. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- cell-cycle linked differences in localization
- co-occurrence with intraflagellar transport markers
- changes in cilia incidence or apparent length in perturbation studies
Variant Considerations
For size-resolved readouts under denaturing conditions, this version helps you focus on expected band patterns and molecular weight regions. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
When interpreting KIAA0586 N-Terminus, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
When interpreting KIAA0586 N-Terminus, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
The denaturing-format version supports deeper biological narratives around KIAA0586 N-Terminus without overcomplicating setup.
- Targets:
- KIAA0586
- Research Area:
- Cell Cycle • Developmental Biology
- Application:
- WB
- Reactivity:
- Human
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the N-terminal region of human KIAA0586 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9BVV6
- Homology:
- Synthetic peptide sequence shows 56.3% homology to mouse sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C