KM11060

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Selleck Chemicals

S6599-5MG

€144,00 EUR
€144,00 EUR
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KM11060 is a modulator of CFTR used in studies of ion-channel pharmacology. In practice, this places the compound in experiments that measure ion conductance, membrane potential, and electrophysiological responses in cell signaling models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By modulating CFTR, KM11060 can be used to examine ion conductance, membrane potential, and electrophysiological responses. This target class is commonly examined through electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping. In cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving CFTR
  • Context-dependent response profiling and mechanism comparison
  • Electrophysiology, ion-flux, and membrane-potential studies
  • Phenotypic profiling in cell signaling models

Overall, KM11060 is appropriate when a defined chemical perturbant is needed to connect CFTR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
CFTR
Target Class:
Ion Channel
Research Area:
Cell Signaling
CAS No.:
774549-97-2
Molecular Weight:
422.33
Formula:
C₁₉H₁₇Cl₂N₃O₂S
SMILES:
C1CN(CCN1C2=C3C=CC(=CC3=NC=C2)Cl)S(=O)(=O)C4=CC=C(C=C4)Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.