Kynurenic acid

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Selleck Chemicals

SKU:S4719-100MG

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Kynurenic acid is an antagonist of NMDAR and Glutamate Receptors and related targets used in studies of Calcium Signaling and Neurotransmission. In practice, this places the compound in experiments that measure calcium flux, excitability, and secretion-linked signaling and synaptic signaling, receptor activity, and neuronal excitability in neuroscience models.

By blocking NMDAR and Glutamate Receptors and related targets, Kynurenic acid can be used to examine calcium flux, excitability, and secretion-linked signaling and synaptic signaling, receptor activity, and neuronal excitability. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving NMDAR and Glutamate Receptors and related targets
  • Pathway perturbation studies connected to Calcium Signaling and Neurotransmission
  • Receptor-blockade and ligand-competition studies
  • Electrophysiology, ion-flux, and membrane-potential studies

Overall, Kynurenic acid is appropriate when a defined chemical perturbant is needed to connect NMDAR and Glutamate Receptors and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
NMDAR • Glutamate Receptors • AChR
Target Class:
Ion Channel
Pathways:
Calcium Signaling • Neurotransmission
Research Area:
Neuroscience
CAS No.:
492-27-3
Molecular Weight:
189.17
Formula:
C₁₀H₇NO₃
SMILES:
C1=CC=C2C(=C1)C(=O)C=C(N2)C(=O)O
InChIKey:
HCZHHEIFKROPDY-UHFFFAOYSA-N
PubChem:
3845
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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