Kynurenic acid
Selleck Chemicals
SKU:S4719-100MG
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Kynurenic acid is an antagonist of NMDAR and Glutamate Receptors and related targets used in studies of Calcium Signaling and Neurotransmission. In practice, this places the compound in experiments that measure calcium flux, excitability, and secretion-linked signaling and synaptic signaling, receptor activity, and neuronal excitability in neuroscience models.
By blocking NMDAR and Glutamate Receptors and related targets, Kynurenic acid can be used to examine calcium flux, excitability, and secretion-linked signaling and synaptic signaling, receptor activity, and neuronal excitability. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving NMDAR and Glutamate Receptors and related targets
- Pathway perturbation studies connected to Calcium Signaling and Neurotransmission
- Receptor-blockade and ligand-competition studies
- Electrophysiology, ion-flux, and membrane-potential studies
Overall, Kynurenic acid is appropriate when a defined chemical perturbant is needed to connect NMDAR and Glutamate Receptors and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- NMDAR • Glutamate Receptors • AChR
- Target Class:
- Ion Channel
- Pathways:
- Calcium Signaling • Neurotransmission
- Research Area:
- Neuroscience
- CAS No.:
- 492-27-3
- Molecular Weight:
- 189.17
- Formula:
- C₁₀H₇NO₃
- SMILES:
- C1=CC=C2C(=C1)C(=O)C=C(N2)C(=O)O
- InChIKey:
- HCZHHEIFKROPDY-UHFFFAOYSA-N
- PubChem:
- 3845
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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