L-NAME HCl

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Selleck Chemicals

SKU:S2877-100MG

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L-NAME HCl is an inhibitor of NOS used in studies of enzyme regulation. In practice, this places the compound in experiments that measure catalytic activity, substrate turnover, and enzymatic regulation in cardiovascular, immunology, and inflammation models.

By inhibiting NOS, L-NAME HCl can be used to examine catalytic activity, substrate turnover, and enzymatic regulation. This target class is commonly examined through enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping. In cardiovascular, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving NOS
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling
  • Phenotypic profiling in cardiovascular, immunology, and inflammation models

Overall, L-NAME HCl is appropriate when a defined chemical perturbant is needed to connect NOS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
NOS
Target Class:
Enzyme
Research Area:
Cardiovascular • Immunology • Inflammation
CAS No.:
51298-62-5
Molecular Weight:
269.69
Formula:
C₇H₁₅N₅O₄·HCl
SMILES:
COC(=O)C(CCCN=C(N)N[N+](=O)[O-])N.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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