L-selectin (SELL or LECAM1 or CD62L) Antibody
BiCell Scientific
SKU:01301-50UL
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About the Target
This antibody is suited for researchers who want to characterize L-selectin and relate it to cell-state biology. L-selectin is a surface or signaling marker used to characterize immune cell subsets and activation states. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Tracking L-selectin can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Context
Experimental perturbations such as cytokine exposure can reshape marker abundance and localization patterns. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- activation-dependent changes across stimulation conditions
- assessment of surface versus internalized pools
- comparisons across differentiation or polarization states
Variant Considerations
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so L-selectin patterns can be compared across experiments without guesswork.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so L-selectin patterns can be compared across experiments without guesswork.
As you refine hypotheses around L-selectin, the regular format format helps keep conclusions tied to preparation context.
- Targets:
- SELL
- Research Area:
- Developmental Biology • Immunology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the C-terminal cytoplasmic region of mouse L-selectin protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P14151
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 73.3% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C