Laminin beta-3 (LAMB3) HiRe Antibody
BiCell Scientific
SKU:05103-50UL
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About the Target
When you need to investigate Laminin beta-3 (LAMB3) with attention to cellular organization, this antibody provides a focused option. Laminin beta-3 is a matrix-interaction protein often examined in migration and morphogenesis models. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol LAMB3.
Research Context
Perturbations that disrupt integrin engagement or actomyosin tension can reshape localization and complex assembly. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- remodeling after changes in substrate or mechanical stress
- effects of adhesion inhibitors or matrix composition
- focal adhesion versus diffuse membrane distribution
Variant Considerations
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Laminin beta-3 patterns can be compared across experiments without guesswork.
When interpreting Laminin beta-3, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
The regular format version supports deeper biological narratives around Laminin beta-3 (LAMB3) without overcomplicating setup.
- Targets:
- LAMB3
- Research Area:
- Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the C-terminal region of mouse laminin beta-3 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q13751
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 88.9% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C