Lamotrigine

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Selleck Chemicals

SKU:S3024-10MG

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Lamotrigine is an inhibitor of Sodium Channels used in studies of Neurotransmission. It is especially relevant in cardiovascular and neuroscience models, where defined compound exposure can be linked to synaptic signaling, receptor activity, and neuronal excitability.

By inhibiting Sodium Channels, Lamotrigine can be used to examine synaptic signaling, receptor activity, and neuronal excitability. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In cardiovascular and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Sodium Channels
  • Pathway perturbation studies connected to Neurotransmission
  • Concentration-response inhibition and target-dependence studies
  • Electrophysiology, ion-flux, and membrane-potential studies

Overall, Lamotrigine is appropriate when a defined chemical perturbant is needed to connect Sodium Channels with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Sodium Channels
Target Class:
Ion Channel
Pathways:
Neurotransmission
Research Area:
Cardiovascular • Neuroscience
CAS No.:
84057-84-1
Molecular Weight:
256.09
Formula:
C₉H₇Cl₂N₅
SMILES:
C1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N
InChIKey:
PYZRQGJRPPTADH-UHFFFAOYSA-N
PubChem:
3878
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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