Lanabecestat (AZD3293)

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Selleck Chemicals

S8193-2MG

€144,00 EUR
€144,00 EUR
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Lanabecestat (AZD3293) is an inhibitor of BACE used in studies of protease biology. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to proteolytic processing and cleavage-dependent signaling in neuroscience models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By inhibiting BACE, Lanabecestat (AZD3293) can be used to examine proteolytic processing and cleavage-dependent signaling. This target class is commonly examined through protease-activity, cleavage, and substrate-processing assays, together with downstream-response mapping. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving BACE
  • Concentration-response inhibition and target-dependence studies
  • Protease-activity, cleavage, and substrate-processing assays
  • Phenotypic profiling in neuroscience models

Overall, Lanabecestat (AZD3293) is appropriate when a defined chemical perturbant is needed to connect BACE with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
BACE
Target Class:
Protease
Research Area:
Neuroscience
CAS No.:
1383982-64-6
Molecular Weight:
412.53
Formula:
C₂₆H₂₈N₄O
SMILES:
CC#CC1=CC(=CN=C1)C2=CC3=C(CC4(C35N=C(C(=N5)N)C)CCC(CC4)OC)C=C2
InChIKey:
WKDNQONLGXOZRG-UHFFFAOYSA-N
PubChem:
57404290
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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