LB42708

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Selleck Chemicals

S7467-5MG

€144,00 EUR
€144,00 EUR
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LB42708 is an inhibitor of KRAS used in studies of MAPK / ERK Signaling. It is especially relevant in cancer, cell signaling, and metabolism models, where defined compound exposure can be linked to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling.

By inhibiting KRAS, LB42708 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. This context is compatible with phosphorylation mapping, pathway-response, and growth assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cancer, cell signaling, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving KRAS
  • Pathway perturbation studies connected to MAPK / ERK Signaling
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in cancer, cell signaling, and metabolism models

Overall, LB42708 is appropriate when a defined chemical perturbant is needed to connect KRAS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
KRAS
Target Class:
Other
Pathways:
MAPK / ERK Signaling
Research Area:
Cancer • Cell Signaling • Metabolism
CAS No.:
226929-39-1
Molecular Weight:
555.46
Formula:
C₃₀H₂₇BrN₄O₂
SMILES:
C1COCCN1C(=O)C2=CN(C=C2C3=CC=CC4=CC=CC=C43)CC5=CN=CN5CC6=CC=C(C=C6)Br
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.