Leptin receptor (LEPR or CD295) Antibody - FFPE Validated
BiCell Scientific
SKU:52095-FFPE-50UL
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About the Target
Bring Leptin receptor into view to explore changes across conditions. Leptin receptor is a signaling node often evaluated by abundance, localization, and modification-dependent states. Focus on trends across conditions rather than single-point snapshots.
In some datasets and protocols, it is referenced by the gene symbol LEPR.
Research Context
Parallel measurement of upstream inputs and downstream readouts can sharpen interpretation of pathway behavior. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Consider these angles when interpreting target-level changes:
- localization shifts between cytoplasm, membrane, and nucleus
- time-resolved changes following stimulation or inhibition
- condition-to-condition comparisons with matched controls
- interaction patterns within multi-protein complexes
Variant Considerations
Because fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
If your study spans multiple model systems, it can help to define a shared reference condition for Leptin receptor so cross-sample contrasts stay meaningful.
When interpreting Leptin receptor, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
When interpreting Leptin receptor, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Select the fixed-section version to keep Leptin receptor interpretation aligned with your workflow goals.
- Targets:
- LEPR
- Research Area:
- Cell Signaling • Developmental Biology • Endocrinology • Immunology • Metabolism
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the C-terminal cytoplasmic region of human LEPR protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P48357
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C