Licogliflozin

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Selleck Chemicals

E8127

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Licogliflozin is an inhibitor of SGLT1 and SGLT2 used in studies of Metabolic Signaling. It is especially relevant in endocrinology and metabolism models, where defined compound exposure can be linked to metabolic regulation, energy sensing, and enzyme-linked homeostasis.

By inhibiting SGLT1 and SGLT2, Licogliflozin can be used to examine metabolic regulation, energy sensing, and enzyme-linked homeostasis. The transporter annotation adds relevance to transport, uptake/efflux, and permeability assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving SGLT1 and SGLT2
  • Pathway perturbation studies connected to Metabolic Signaling
  • Concentration-response inhibition and target-dependence studies
  • Transport, uptake/efflux, and permeability assays

Overall, Licogliflozin is appropriate when a defined chemical perturbant is needed to connect SGLT1 and SGLT2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
SGLT1 • SGLT2
Target Class:
Transporter
Pathways:
Metabolic Signaling
Research Area:
Endocrinology • Metabolism
CAS No.:
1291094-73-9
Molecular Weight:
416.46
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.