Lithocholic acid

    1 0

    Selleck Chemicals

    S4003-50MG

    €144,00 EUR
    €144,00 EUR
    Sale Sold out
    Taxes included. Shipping calculated at checkout.
    Size
    View full details

    Lithocholic acid is an agonist of FXR and Vitamin D Receptor and related targets used in studies of Hormone Signaling and Metabolic Signaling. In practice, this places the compound in experiments that measure ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology and metabolism models.

    By activating FXR and Vitamin D Receptor and related targets, Lithocholic acid can be used to examine ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

    Research Applications

    • Target-focused assays involving FXR and Vitamin D Receptor and related targets
    • Pathway perturbation studies connected to Hormone Signaling and Metabolic Signaling
    • Agonist-response and downstream signaling studies
    • Reporter-gene, receptor-binding, and transcriptional assays

    Overall, Lithocholic acid is appropriate when a defined chemical perturbant is needed to connect FXR and Vitamin D Receptor and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

    Targets:
    FXR • Vitamin D Receptor • PXR
    Target Class:
    Nuclear Receptor
    Pathways:
    Hormone Signaling • Metabolic Signaling
    Research Area:
    Endocrinology • Metabolism
    CAS No.:
    434-13-9
    Molecular Weight:
    376.57
    Formula:
    C₂₄H₄₀O₃
    SMILES:
    CC(CCC(=O)O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C
    Storage Temperature:
    -20°C

    For Research Use Only. Not intended for diagnostic or therapeutic use.
    Products may be subject to intellectual property rights.

    The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.