Lixisenatide

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Selleck Chemicals

SKU:S8517-1MG

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Lixisenatide is an agonist of Glucagon Receptor and GLP-1 Receptor used in studies of GPCR Signaling and Metabolic Signaling. It is especially relevant in endocrinology and metabolism models, where defined compound exposure can be linked to receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis.

By activating Glucagon Receptor and GLP-1 Receptor, Lixisenatide can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Glucagon Receptor and GLP-1 Receptor
  • Pathway perturbation studies connected to GPCR Signaling and Metabolic Signaling
  • Agonist-response and downstream signaling studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, Lixisenatide is appropriate when a defined chemical perturbant is needed to connect Glucagon Receptor and GLP-1 Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Glucagon Receptor • GLP-1 Receptor
Target Class:
GPCR
Pathways:
GPCR Signaling • Metabolic Signaling
Research Area:
Endocrinology • Metabolism
CAS No.:
320367-13-3
Molecular Weight:
4858.49
Formula:
C₂₁₅H₃₄₇N₆₁O₆₅S
SMILES:
CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NCC(=O)NCC(=O)N3CCCC3C(=O)NC(CO)C(=O)NC(CO)C(=O)NCC(=O)NC(C)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)N)NC(=O)C(CC6=CC=CC=C6)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C(CC8=CNC=N8)N
InChIKey:
XVVOERDUTLJJHN-UHFFFAOYSA-N
PubChem:
131704317
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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