LLGL1 (LGL1) Antibody - FFPE Validated

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BiCell Scientific

SKU:00271-FFPE-50UL

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Size
Blocking Peptide
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Protein Function

Designed to help you investigate LLGL1, this antibody supports studies where protein context matters. LLGL1 is a signaling protein that can relay information through phosphorylation and complex assembly. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.

Monitoring LLGL1 alongside context markers can improve interpretation when phenotypes are subtle.

Experimental Applications

When comparing conditions, consistent sample handling and normalization are key for meaningful contrasts. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.

In practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy.

Common experimental questions that benefit from target tracking include:

  • interaction patterns within multi-protein complexes
  • localization shifts between cytoplasm, membrane, and nucleus
  • condition-to-condition comparisons with matched controls

Workflow Perspective

Because fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.

When interpreting LLGL1, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

For challenging targets, pairing LLGL1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

As you refine hypotheses around LLGL1, the fixed-section format helps keep conclusions tied to preparation context.

Targets:
LLGL1
Research Area:
Cell Signaling • Developmental Biology
Application:
IHC-P
Reactivity:
Human • Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (15-aa) derived from the C-terminal region of mouse LLGL1 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
Q15334
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 93.3% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C