LM22B-10

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Selleck Chemicals

S6760-5MG

€193,00 EUR
€193,00 EUR
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LM22B-10 is an activator of Trk Receptors and AKT and related targets used in studies of PI3K-Akt-mTOR Signaling and MAPK / ERK Signaling. It is especially relevant in cancer, cell signaling, and metabolism models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs and mitogenic kinase cascades, proliferation control, and differentiation-linked signaling.

By activating Trk Receptors and AKT and related targets, LM22B-10 can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Trk Receptors and AKT and related targets
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and MAPK / ERK Signaling
  • Gain-of-function pathway-activation studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, LM22B-10 is appropriate when a defined chemical perturbant is needed to connect Trk Receptors and AKT and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Trk Receptors • AKT • ERK
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling • MAPK / ERK Signaling
Research Area:
Cancer • Cell Signaling • Metabolism • Neuroscience
CAS No.:
342777-54-2
Molecular Weight:
485.01
Formula:
C₂₇H₃₃ClN₂O₄
SMILES:
C1=CC(=CC=C1C(C2=CC=C(C=C2)N(CCO)CCO)C3=CC=C(C=C3)Cl)N(CCO)CCO
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.