LMK-235
Selleck Chemicals
SKU:S7569-10MG
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LMK-235 is an inhibitor of HDAC used in studies of DNA Damage Response and Epigenetic Regulation. In practice, this places the compound in experiments that measure checkpoint activation, DNA repair, and genome-stability control and chromatin-state control, histone modification, and transcriptional regulation in cancer, dna damage / repair, and epigenetics models.
By inhibiting HDAC, LMK-235 can be used to examine checkpoint activation, DNA repair, and genome-stability control and chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In cancer, dna damage / repair, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving HDAC
- Pathway perturbation studies connected to DNA Damage Response and Epigenetic Regulation
- Concentration-response inhibition and target-dependence studies
- Chromatin, epigenetic, and gene-expression profiling
Overall, LMK-235 is appropriate when a defined chemical perturbant is needed to connect HDAC with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, dna damage / repair, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- HDAC
- Target Class:
- Epigenetic Regulator
- Pathways:
- DNA Damage Response • Epigenetic Regulation
- Research Area:
- Cancer • DNA Damage / Repair • Epigenetics
- CAS No.:
- 1418033-25-6
- Molecular Weight:
- 294.35
- Formula:
- C₁₅H₂₂N₂O₄
- SMILES:
- CC1=CC(=CC(=C1)C(=O)NOCCCCCC(=O)NO)C
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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