LRP1 (CD91) Antibody - FFPE Validated

Protein Function

Use this antibody to analyze LRP1 (CD91) in your model system. LRP1 is a junctional protein that coordinates adhesion with cytoskeletal anchoring. Look for shifts in distribution that track with phenotype changes.

In some datasets and protocols, it is referenced by the gene symbol CD91.

Experimental Applications

Shifts in junction organization can accompany migration, tissue morphogenesis, and altered mechanical tension. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

Target-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing. Blood-brain barrier models often monitor junction regulation alongside permeability-focused measurements.

Common experimental questions that benefit from target tracking include:

• changes in complex assembly with scaffold or adaptor proteins
• comparative profiling across cell states or perturbations
• subcellular redistribution at contact sites versus cytoplasm
• co-localization patterns with cytoskeletal elements

Workflow Perspective

In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.

For challenging targets, pairing LRP1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

For challenging targets, pairing LRP1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

Choose the fixed-section option when you want LRP1 (CD91) results aligned to your sample format.