LY341495

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Selleck Chemicals

S8121

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LY341495 is an antagonist of Glutamate Receptors used in studies of Calcium Signaling and GPCR Signaling. In practice, this places the compound in experiments that measure calcium flux, excitability, and secretion-linked signaling and receptor-driven second-messenger signaling and desensitization dynamics in neuroscience models.

By blocking Glutamate Receptors, LY341495 can be used to examine calcium flux, excitability, and secretion-linked signaling and receptor-driven second-messenger signaling and desensitization dynamics. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Glutamate Receptors
  • Pathway perturbation studies connected to Calcium Signaling and GPCR Signaling
  • Receptor-blockade and ligand-competition studies
  • Electrophysiology, ion-flux, and membrane-potential studies

Overall, LY341495 is appropriate when a defined chemical perturbant is needed to connect Glutamate Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Glutamate Receptors
Target Class:
Ion Channel
Pathways:
Calcium Signaling • GPCR Signaling
Research Area:
Neuroscience
CAS No.:
201943-63-7
Molecular Weight:
353.37
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.