LYN (JTK8) Antibody
BiCell Scientific
SKU:52418-50UL
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Scientific Overview
Designed to help you explore LYN (JTK8), this antibody supports studies where protein context matters. LYN is a signaling protein that can relay information through phosphorylation and complex assembly. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol JTK8.
Research Relevance
Perturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling. In oncology research models, expression shifts can accompany changes in adhesion, signaling, or differentiation state.
When building a narrative around the target, it helps to track:
- interaction patterns within multi-protein complexes
- localization shifts between cytoplasm, membrane, and nucleus
- condition-to-condition comparisons with matched controls
Application-Specific Context
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
When interpreting LYN, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Use the regular format variant when your project demands LYN (JTK8) readouts that respect preparation constraints.
- Targets:
- LYN
- Research Area:
- Cancer • Cell Signaling
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the N-terminal region of mouse LYN protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P07948
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 75% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.