MARK4 inhibitor 1

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Selleck Chemicals

SKU:E2818-5MG

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MARK4 inhibitor 1 is an inhibitor of AMPK used in studies of PI3K-Akt-mTOR Signaling and Cell Cycle Regulation. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint control, mitotic progression, and proliferation timing in autophagy, cancer, and cell cycle models.

By inhibiting AMPK, MARK4 inhibitor 1 can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint control, mitotic progression, and proliferation timing. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving AMPK
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and Cell Cycle Regulation
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, MARK4 inhibitor 1 is appropriate when a defined chemical perturbant is needed to connect AMPK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
AMPK
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling • Cell Cycle Regulation
Research Area:
Autophagy • Cancer • Cell Cycle • Cell Signaling
CAS No.:
2271081-58-2
Molecular Weight:
390.4
Formula:
C₂₀H₁₈N₆O₃
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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