Megestrol Acetate

1 1

Selleck Chemicals

S1304-50MG

€144,00 EUR
€144,00 EUR
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Megestrol Acetate is an inhibitor of Estrogen/Progesterone Receptors and Androgen Receptor used in studies of Hormone Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to ligand-dependent transcriptional programs and endocrine regulation in cancer and endocrinology models.

By inhibiting Estrogen/Progesterone Receptors and Androgen Receptor, Megestrol Acetate can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In cancer and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Estrogen/Progesterone Receptors and Androgen Receptor
  • Pathway perturbation studies connected to Hormone Signaling
  • Concentration-response inhibition and target-dependence studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, Megestrol Acetate is appropriate when a defined chemical perturbant is needed to connect Estrogen/Progesterone Receptors and Androgen Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Estrogen/Progesterone Receptors • Androgen Receptor
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling
Research Area:
Cancer • Endocrinology
CAS No.:
595-33-5
Molecular Weight:
384.51
Formula:
C₂₄H₃₂O₄
SMILES:
CC1=CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C
InChIKey:
URXWVWVPMJSAJD-KOORYGTMSA-N
PubChem:
11683
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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