Memantine HCl

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Selleck Chemicals

S2043-200MG

€144,00 EUR
€144,00 EUR
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Memantine HCl is an antagonist of NMDAR used in studies of Calcium Signaling. It is especially relevant in neuroscience models, where defined compound exposure can be linked to calcium flux, excitability, and secretion-linked signaling. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By blocking NMDAR, Memantine HCl can be used to examine calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving NMDAR
  • Pathway perturbation studies connected to Calcium Signaling
  • Receptor-blockade and ligand-competition studies
  • Electrophysiology, ion-flux, and membrane-potential studies

Overall, Memantine HCl is appropriate when a defined chemical perturbant is needed to connect NMDAR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
NMDAR
Target Class:
Ion Channel
Pathways:
Calcium Signaling
Research Area:
Neuroscience
CAS No.:
41100-52-1
Molecular Weight:
215.76
Formula:
C₁₂H₂₁N·HCl
SMILES:
CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.