Methylene Blue trihydrate

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Selleck Chemicals

SKU:E4805-100MG

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Methylene Blue trihydrate is an inhibitor of NOS and MAO-A used in studies of GPCR Signaling and Metabolic Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis in cardiovascular, inflammation, and metabolism models.

By inhibiting NOS and MAO-A, Methylene Blue trihydrate can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cardiovascular, inflammation, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving NOS and MAO-A
  • Pathway perturbation studies connected to GPCR Signaling and Metabolic Signaling
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Methylene Blue trihydrate is appropriate when a defined chemical perturbant is needed to connect NOS and MAO-A with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, inflammation, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
NOS • MAO-A
Target Class:
Enzyme
Pathways:
GPCR Signaling • Metabolic Signaling
Research Area:
Cardiovascular • Inflammation • Metabolism • Neuroscience
CAS No.:
7220-79-3
Molecular Weight:
373.90
Formula:
C₁₆H₁₈N₃S·Cl·3H₂O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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